Efficient conversion of 6-cyanopurines into 6-alkoxyformimidoylpurines
نویسندگان
چکیده
منابع مشابه
Efficient conversion of 6-cyanopurines into 6-alkoxyformimidoylpurines.
An extremely simple method for the selective synthesis of 9-aryl and 9-alkyl 6-alkoxy or 6-alkoxyformimidoylpurines from the corresponding 6-cyanopurines is described. The reaction is carried out with methanol or ethanol in the presence of DBU. At room temperature, nucleophilic attack by the primary alcohol occurs selectively on the cyano carbon atom, leading to 6-alkoxyformimidoylpurines in go...
متن کاملEnzymatic conversion of 6-nitroquinoline to the fluorophore 6-aminoquinoline selectively under hypoxic conditions.
There is substantial interest in small molecules that can be used to detect or kill the hypoxic (low oxygen) cells found in solid tumors. Nitroaryl moieties are useful components in the design of hypoxia-selective imaging agents and prodrugs because one-electron reductases can convert the nitroaryl group to nitroso, hydroxylamino, and amino metabolites selectively under low oxygen conditions. H...
متن کامل3-Hydroxypropylammonium acetate (HPAA) ionic liquid: An effective acidic media in efficient conversion of anilines into aryl isocyanates
A simple and mild procedure for the conversion of anilines into aryl isocyanates is described using the 3-hydroxypropylammonium acetate (HPAA) ionic liquid as a novel and efficient media has been explored in the synthesis of aryl isocyanates from the reaction of substituted urea with sodium nitrite in a water immiscible solvent. This ionic liquid can be easily recovered and reused for many time...
متن کامل6 Green and Efficient RAN Architectures
The explosive increase of capacity demand has resulted in more dense deployments involving a growing number of BSs. To make future mobile networks sustainable from an economic viewpoint, they should provide more while simultaneously cost less. Installing smaller cells in areas where infrastructure can provide the required backhaul connectivity is the current natural evolution of radio access ne...
متن کامل3-Hydroxypropylammonium acetate (HPAA) ionic liquid: An effective acidic media in efficient conversion of anilines into aryl isocyanates
A simple and mild procedure for the conversion of anilines into aryl isocyanates is described using the 3-hydroxypropylammonium acetate (HPAA) ionic liquid as a novel and efficient media has been explored in the synthesis of aryl isocyanates from the reaction of substituted urea with sodium nitrite in a water immiscible solvent. This ionic liquid can be easily recovered and reused for many time...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Org. Biomol. Chem.
سال: 2004
ISSN: 1477-0520,1477-0539
DOI: 10.1039/b400171k